ZADITOR® Eye Drops—The all-day or all-night solution to itchy eyes

Take control of itchy eyes all-day or all-night with ZADITOR® Eye Drops—the first non-prescription eye drop strong enough to last up to 12 hours with just one drop.

Many over-the-counter eye allergy drops (containing both an antihistamine and a decongestant) provide only short term relief and require frequent re-dosing. With ZADITOR® Eye Drops, there’s no need to re-dose during the day. Just one powerful drop lasts up to 12 hours. So you no longer need to carry eye drops everywhere you go.

Available over-the-counter in original prescription strength

People everywhere can get original prescription strength ZADITOR® Eye Drops without a prescription. Available over-the-counter at retail outlets nationwide, ZADITOR® Eye Drops contain the same prescription strength formula that physicians have known and trusted since 1999.

ZADITOR® Eye Drops vs. other over-the-counter allergy eye drops

Many over-the-counter allergy eye drops contain an antihistamine and a vasoconstrictor. Vasoconstrictors (decongestants) work by constricting blood vessels (vasoconstriction) to reduce the appearance of redness in the eye. These products can cause rebound redness for a period of time after discontinuation when overused.1

ZADITOR® Eye Drops antihistamine eye drops for itchy eye relief are unlike most over-the-counter eye allergy medications which contain a vasoconstrictor. Instead, ZADITOR® Eye Drops contains an antihistamine that relieves the itch in minutes and keeps working for up to 12 hours—with just one drop!

Important differences between ZADITOR® Eye Drops and leading over-the-counter eye allergy drops

How ZADITOR® Eye Drops work

ZADITOR® EYE DROPS block and prevent the release of histamine in three ways.
  • 1. Works as an antihistamine to relieve the itch in minutes.
  • 2. Works as a mast cell stabilizer to prevent the itch from returning for up to 12
  • 3. Late-phase reactions are stopped by preventing the release of chemical
           mediators, called eosinophils.4

How to use ZADITOR® Eye Drops

It’s important to wash your hands before applying eye drops.

TILT your head back and look upward. Use your fingers to gently press the skin just beneath the lower eyelid, then pull the lower eyelid away from the eye to make a space.

HOLD the dropper above your eye and squeeze one drop into this space. Be careful not to touch your eyelid or surrounding area with the dropper tip of the bottle.

RELEASE your eyelid and close your eye gently, then blink to allow the drop to spread around the eye.

BLOT around your eye with a tissue to remove any excess.

The recommended dose is 1 drop in the affected eye(s) twice a day. If you wear contact lenses, wait at least 10 minutes after using ZADITOR® Eye Drops before you insert your lenses.

1Soparkar CN, Wilhelmus KR, Koch DD, et al. Acute and chronic conjunctivitis due to over-the-counter ophthalmic decongestants. Arch Opthalmol. 1997;115(1):34–8.
2 Schoch C. In Vitro Inhibition of Human Conjunctival Mast-Cell Degranulation by Ketotifen.
J Ocul Pharmacol Ther. February 2003;19(1):75–81.
3Greiner JV. Minno G. A placebo-controlled comparison of ketotifen fumarate and nedocromil sodium ophthalmic solutions for the prevention of ocular itching with the conjunctival allergen challenge model. Clin Ther. July 2003;25(7):1988–2005.
4Woerly G, Loiseau S, Loyens M, et al. Inhibitory effects of ketotifen on eotaxin-dependent activation of eosinophils: consequences for allergic eye diseases. Allergy. 2003;58(5):397–406.